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LONG-TERM EFFECTS OF PATIENTS AFTER AM-PUTATION OF THE LOWER EXTREMITY ON THE GROUND OF A DIABETIC ULCER. SYSTEMATIC LITERATURE REVIEW.

Aggeliki Vandorou, Εvrydiki Kaba, Martha Kelesi, Georgia Fasoi


Sunday, January 1, 2023

Publication year:

2023

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Keywords index:

Pages: 68-79

DOI: 10.5281/zenodo.10461722

Abstract:

Introduction: Diabetic foot ulcers are the leading cause of non-traumatic amputation of the lower extremities, often followed by non-healing ulcers and are increasingly recognized as a serious, global public health problem. The recurrence rates of diabetic foot ulcers are high and for this reason the prevention of diabetic foot ulcers is of utmost importance in reducing the risks for the patient and the financial burden of the health systems, but also of society.Purpose: The purpose of this study was to systematically review the literature to investigate the long-term consequences of patients after lower extremity amputation on the ground of a diabetic ulcer. Methodology: This is a systematic review of the literature. The literature was searched in the Pubmed database. The keywords Diabetes, Diabetes Mellitus, Foot Ulcers, Amputations, Outcomes were used. Articles that were primary studies, included adult patients with diabetic lower extremity ulcers before amputation, were written in English or Greek and were published in the last decade. Results: Totally, 5 articles included. Risk factors for lower limb amputation found include previous lower limb amputation, peripheral arterial disease, ulcer of the front leg, high grade Wanger, advanced age, chronic kidney disease, decreased plasma albumin, traumatic brain injury, dialysis. The weighted mean recurrent amputation was 12.5%, 22.3% and 47.1% at 1, 3 and 5 years respectively. The weighted average mortality at 1, 3 and 5 years was 12.26%, 24.4% and 35.17% respectively. Conclusions: Patients with diabetic lower extremity ulcer should be monitored and evaluated regularly, due to the high risk of amputation and the consequent adverse effects.

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