QUALITY OF LIFE OF PATIENTS WITH TYPE 3C DIA-BETES MELLITUS AFTER PARTIAL, TOTAL PANCRE-ATECTOMY AND PANCREATICODUODENECTOMY - SYSTEMATIC REVIEW
Georgia Kimouliati, Maria Bourazani, Antonia Kalogianni, Eleni Dokoutsidou, Demetrios Korkolis, Εugenia Vlachou
Saturday, October 1, 2022
Publication year:
2022
Authors:
- Kimouliati Georgia, Nurse MSc, Department of Nursing, University of West Attica
- Bourazani Maria, RN,MSc,PhDc , Department of Nursing, University of West Attica, Anesthesiology Department,”Saint Savvas” Hospital,Athens
- Kalogianni Antonia, Associate Professor,Department of Nursing,University of West Attica Greece
- Dokoutsidou Eleni, Associate Professor, University of West Attica, Department of Nursing, Athens, Greece
- Korkolis Demetrios, Director of the Surgical Department, ,”Saint Savvas” Hospital,Athens
- Vlachou Εugenia, Professor, Department of Nursing, University of West Attica, Athens, Greece
Keywords index:
- Diabetes mellitus
- pancreatogenic diabetes
- pancreatic cancer
- quality of life
- total pancreatectomy
- partial pancreatectomy
- pancreaticoduodenectomy
Pages: 402-415
Abstract:
Introduction: Type 3c diabetes mellitus, also known as pancreatogenic diabetes, occurs after partial or total pancreatectomy or pancreaticoduodenectomy. Pancreatogenic diabetes in combination with the pancreatic cancer and the postoperative condition of patients who undergo pancreatectomy, affects their quality of life. Aim: The aim was the systematic review of the literature in order to investigate quality of life of patients with type 3c diabetes mellitus after partial, total pancreatectomy and pancreaticoduodenectomy. Material and Method: A systematic review was undertaken of current literature, searching to Medline (Pubmed), Google Scholar και Scopus from May 2021 to April 2022. Inclusion criteria of the 6 studies of this work were the primary studies in english and greek language, published after 2012, with a sample of individuals who underwent pancreatectomy and diagnosed with type 3c diabetes mellitus. Results: Patients with type 3c diabetes mellitus after pancreatectomy had a comparable diabetes and cancer related quality of life. However, patients who underwent total pancreatectomy had slightly worse physical and emotional function, longer duration of fatigue at daily activities, dysfunction of social relations, insomnia, more severe gastrointestinal symptoms such as indigestion and flatulence and more common hypoglycemic episodes than in patients underwent partial pancreatectomy or pancreaticoduodenectomy. In addition, both the growing age of patients and the pancreatic insufficiency adversely affect the quality of life. Conclusion: Patients who undergo total pancreatectomy do not show statistically significant difference in overall quality of life compared to patients who undergo partial pancreatectomy and pancreaticoduodenectomy. However, pathological factors associated with total pancreatectomy postoperatively such as pancreatogenic diabetes, contribute to the limitation of this kind of surgery and it is recommended to be applied with specific criteria and the patient survival as the aim.
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